Ding S.,104 Black Engineering |
Cargill A.A.,104 Black Engineering |
Medintz I.L.,Center for Bio Molecular Science and Engineering |
Claussen J.C.,104 Black Engineering
Current Opinion in Biotechnology | Year: 2015
The efficiency and selectivity of enzymatic catalysis is useful to a plethora of industrial and manufacturing processes. Many of these processes require the immobilization of enzymes onto surfaces, which has traditionally reduced enzyme activity. However, recent research has shown that the integration of nanoparticles into enzyme carrier schemes has maintained or even enhanced immobilized enzyme performance. The nanoparticle size and surface chemistry as well as the orientation and density of immobilized enzymes all contribute to the enhanced performance of enzyme-nanoparticle conjugates. These improvements are noted in specific nanoparticles including those comprising carbon (e.g., graphene and carbon nanotubes), metal/metal oxides and polymeric nanomaterials, as well as semiconductor nanocrystals or quantum dots. © 2015 Elsevier Ltd.